Article
Genome-wide association analysis for multiple continuous secondary phenotypes.
American journal of human genetics - 2 May 2013
Schifano Elizabeth D, Li Lin, Christiani David C, Lin Xihong
Abstract excerpt
There is increasing interest in the joint analysis of multiple phenotypes in genome-wide association studies (GWASs), especially for the analysis of multiple secondary phenotypes in case-control studies and in detecting pleiotropic effects. Multiple phenotypes often measure the same underlying trait. By taking advantage of similarity across phenotypes, one could potentially gain statistical power in association...
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