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Article

Proximal tubule glutamine synthetase expression is necessary for the normal response to dietary protein restriction.

American journal of physiology. Renal physiology - 1 Jul 2017

Lee Hyun-Wook, Osis Gunars, Handlogten Mary E, Verlander Jill W, Weiner I David

Abstract excerpt

Dietary protein restriction has multiple benefits in kidney disease. Because protein intake is a major determinant of endogenous acid production, it is important that net acid excretion changes in parallel during changes in dietary protein intake. Dietary protein restriction decreases endogenous acid production and decreases urinary ammonia excretion, a major component of net acid excretion. Glutamine synthetase...

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Identifiers

PMID: 28331060
DOI: 10.1152/ajprenal.00048.2017
PMCID: PMC5538840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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