Article
Renal expression of Na+-phosphate cotransporter mRNA and protein: effect of the Gy mutation and low phosphate diet.
Pflugers Archiv : European journal of physiology - 1 Apr 1996
Beck L, Tenenhouse H S, Meyer R A, Meyer M H, Biber J, Murer H
Abstract excerpt
The X-linked Gy mutation is closely linked, but not allelic, to Hyp and is characterized by rickets, hypophosphatemia, decreased renal tubular maximum for phosphate (Pi) reabsorption (TmP) and a specific reduction in renal brush-border membrane (BBM) Na+-Pi cotransport. Gy mice, like their normal...
Topics
- Animals
- Carrier Proteins
- Female
- Ion Transport
- Kidney
- Male
- Mice
- Mice, Mutant Strains
- Mutation
- Phosphates
- Phosphorus, Dietary
- RNA, Messenger
- Rats
- Rickets
- Sodium
- Sodium-Phosphate Cotransporter Proteins
- Symporters
- X Chromosome