Article
Renal expression of Na+-phosphate cotransporter mRNA and protein: effect of the Gy mutation and low phosphate diet.
Pflugers Archiv : European journal of physiology - 1 Apr 1996
Beck L, Tenenhouse H S, Meyer R A, Meyer M H, Biber J, Murer H
Abstract excerpt
The X-linked Gy mutation is closely linked, but not allelic, to Hyp and is characterized by rickets, hypophosphatemia, decreased renal tubular maximum for phosphate (Pi) reabsorption (TmP) and a specific reduction in renal brush-border membrane (BBM) Na+-Pi cotransport. Gy mice, like their normal littermates, respond to a low-Pi diet with an increase in BBM Na+-Pi cotransport, but fail to show an adaptive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.