Article
Randomized controlled trial: lisinopril reduces proteinuria, ammonia, and renal polypeptide tubular catabolism in patients with chronic allograft nephropathy.
Transplantation - 15 Jan 2010
Amara Alieu B, Sharma Asheesh, Alexander John L, Alfirevic Ana, Mohiuddin Atif, Pirmohamed Munir, Close Graeme L, Grime Steve, Maltby Paul, Shawki Howida, Heyworth Sally, Shenkin Alan, Smith Linda, Sharma Ajay K, Hammad Abdel, Rustom Rana
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme inhibitors in native nephropathies reduce proteinuria and delay progression to renal failure. Data in renal transplantation remain limited. A negative effect on glomerular filtration rate was concluded in a recent systematic review. METHODS: In this novel randomized controlled trial, 47 patients with chronic allograft nephropathy, severe renal impairment, and more than or...
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