Renal acid-base regulation: new insights from animal models.

doi:10.1007/s00424-014-1669-x

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Article

Renal acid-base regulation: new insights from animal models.

Pflugers Archiv : European journal of physiology - 1 Aug 2015

Eladari Dominique, Kumai Yusuke

Abstract excerpt

Because majority of biological processes are dependent on pH, maintaining systemic acid-base balance is critical. The kidney contributes to systemic acid-base regulation, by reabsorbing HCO3 (-) (both filtered by glomeruli and generated within a nephron) and acidifying urine. Abnormalities in those processes will eventually lead to a disruption in systemic acid-base balance and provoke metabolic acid-base...

Topics

Animals
Disease Models, Animal
Genotype
Humans
Kidney
Membrane Transport Proteins
Mice, Transgenic
Models, Biological
Phenotype
Renal Elimination
Renal Reabsorption
Water-Electrolyte Balance
Water-Electrolyte Imbalance

Source

Open in PubMed

Identifiers

PMID: 25515081
DOI: 10.1007/s00424-014-1669-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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