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Article

Association of NR1I2 gene polymorphisms and time of progression to AIDS.

Memorias do Instituto Oswaldo Cruz - 1 Apr 2017

Medeiros Rúbia Marília de, Menti Carolina Fialho, Benelli Jéssica Louise, Matte Maria Cristina Cotta, Melo Marineide Gonçalves de, Almeida Sabrina Esteves de Matos, Fiegenbaum Marilu

Abstract excerpt

BACKGROUND: The time of progression towards AIDS can vary greatly among seropositive patients, and may be associated with host genetic variation. The NR1I2 (PXR) gene, a ligand-activated transcription factor, regulates the transcription immune pathway genes and can therefore be targets of viral replication mechanisms influencing time of progression to AIDS. OBJECTIVE: To verify the association of single...

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PMID: 28327790
DOI: 10.1590/0074-02760160382
PMCID: PMC5354613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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