Article
Protective effects of IL4-589T and RANTES-28G on HIV-1 disease progression in infected Thai females.
AIDS (London, England) - 9 Jan 2006
Wichukchinda Nuanjun, Nakayama Emi E, Rojanawiwat Archawin, Pathipvanich Panita, Auwanit Wattana, Vongsheree Suthon, Ariyoshi Koya, Sawanpanyalert Pathom, Shioda Tatsuo
Abstract excerpt
OBJECTIVE: To evaluate the effect of polymorphisms in interleukin-4 (IL4) and RANTES promoters on disease progression in HIV-1 infected Thais. DESIGN: Antiretroviral (ARV) drug-free HIV-1 infected females from the prospective cohort. METHODS: A total of 246 DNA samples were genotyped for IL4 and RANTES promoter polymorphisms by PCR-RFLP. Associations of genotype with HIV-1 disease progression were assessed with...
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