Article
Brief Report: CYP27B1 rs10877012 T Allele Was Linked to Non-AIDS Progression in ART-Naïve HIV-Infected Patients: A Retrospective Study.
Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2020
Jiménez-Sousa María Angeles, Jiménez José Luis, Bellón José María, Fernández-Rodríguez Amanda, Iribarren Jose Antonio, López-Cortés Luís Fernando, Olalla-Sierra Julián, Martín-Rodrigo María Dolores, Muñoz-Fernández María Ángeles, Resino Salvador
Abstract excerpt
BACKGROUND: HIV/AIDS progression is linked to vitamin D, which is regulated by several key cytochromes P450 (CYP). Single nucleotide polymorphisms (SNPs) in CYP genes influence vitamin D metabolism and serum levels. The objective of this study was to evaluate the association between CYP SNPs and the clinical AIDS progression in antiretroviral treatment (ART)-naïve HIV-infected patients. METHODS: We performed a...
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