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Article

Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression.

Genes and immunity - 1 Dec 2005

Gaudieri S, DeSantis D, McKinnon E, Moore C, Nolan D, Witt C S, Mallal S A, Christiansen F T

Abstract excerpt

Variation in the host response to infection by pathogens including HIV-1 may be conferred by polymorphic genetic factors such as HLA and killer immunoglobulin-like receptors (KIR) genes. Here, we examined KIR and HLA genotype effects on pretreatment viral load, rate of CD4(+) T-cell decline and progression to AIDS among adult HIV-1-infected patients within the Western Australian HIV Study Cohort. In this study,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16121209
DOI: 10.1038/sj.gene.6364256

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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