Article
Risk association of BST2 gene variants with disease progression in HIV-1 infected Indian cohort.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2020
Gupte Divyambari S, Patil Amol, Selvaa Kumar C, Pandey Sudhanshu, Achrekar Swati K, Paranjape Ramesh S, Jagtap Dhanashree D
Abstract excerpt
Bone marrow stromal cell antigen 2 (BST2) is an interferon induced host restriction factor for HIV-1 that blocks the release of nascent virions from infected T cells. We aimed to characterize BST2 gene variants in HIV-1 positive individuals in Indian cohort and study the association of these variants with disease progression in long term non progressors (LTNPs) and progressors. Archived samples of 32 LTNPs, 17...
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