Article
Associations of polymorphisms in the candidate genes for Alzheimer's disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance.
Molecular biology reports - 1 Apr 2017
Vacínová Gabriela, Vejražková D, Lukášová P, Lischková O, Dvořáková K, Rusina R, Holmerová I, Vaňková H, Včelák J, Bendlová B, Vaňková M
Abstract excerpt
Alzheimer's disease (AD) is the most common type of dementia, with a prevalence that is rising every year. AD is associated with type 2 diabetes mellitus (T2DM) and insulin resistance, and is therefore sometimes called "type 3 diabetes mellitus". The aim of this study was to examine whether the variants of some candidate genes involved in the development of AD, namely BIN1 (rs744373), CLU (rs11136000), CR1...
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