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Article

rs3851179 Polymorphism at 5' to the PICALM Gene is Associated with Alzheimer and Parkinson Diseases in Brazilian Population.

Neuromolecular medicine - 1 Sept 2017

Santos-Rebouças Cíntia Barros, Gonçalves Andressa Pereira, Dos Santos Jussara Mendonça, Abdala Bianca Barbosa, Motta Luciana Branco, Laks Jerson, de Borges Margarete Borges, de Rosso Ana Lúcia Zuma, Pereira João Santos, Nicaretta Denise Hack, Pimentel Márcia Mattos Gonçalves

Abstract excerpt

Alzheimer's (AD) and Parkinson's diseases (PD) share clinical and pathological features, suggesting that they could have common pathogenic mechanisms, as well as overlapping genetic modifiers. Here, we performed a case-control study in a Brazilian population to clarify whether the risk of AD and PD might be influenced by shared polymorphisms at PICALM (rs3851179), CR1 (rs6656401) and CLU (rs11136000) genes, which...

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Share to Age of Onset
Share to Apolipoprotein E4
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Share to Clusterin
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Share to Monomeric Clathrin Assembly Proteins
Share to Parkinson Disease
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Source

Identifiers

PMID: 28567584
DOI: 10.1007/s12017-017-8444-z

Genes

APOE
PICALM
CLU

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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rs3851179 Polymorphism at 5' to the PICALM Gene is Associated with Alzheimer and Parkinson Diseases in Brazilian Population.PMID 28567584Read ↗

Correlation of PICALM polymorphism rs3851179 with Alzheimer's disease among Caucasian and Chinese populations: a meta-analysis and systematic review.Semantic proximity Read ↗

Association of MTHFR and PICALM polymorphisms with Alzheimer's disease.Semantic proximity Read ↗

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PICALM rs3851179 Variant Confers Susceptibility to Alzheimer's Disease in Chinese Population.Semantic proximity Read ↗

rs3851179G>A in PICALM is Protective Against Alzheimer's Disease in Five Different Countries Surrounding the Mediterranean.Semantic proximity Read ↗

PICALM gene rs3851179 polymorphism contributes to Alzheimer's disease in an Asian population.Semantic proximity Read ↗

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.Semantic proximity Read ↗

CLU rs9331888 Polymorphism Contributes to Alzheimer's Disease Susceptibility in Caucasian But Not East Asian Populations.Semantic proximity Read ↗

Association of Alzheimer's disease risk variants on the PICALM gene with PICALM expression, core biomarkers, and feature neurodegeneration.Semantic proximity Read ↗

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.Semantic proximity Read ↗

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