Article
Updated Meta-Analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 Variants in Alzheimer's Disease.
Journal of molecular neuroscience : MN - 1 Mar 2018
Almeida Jucimara Ferreira Figueiredo, Dos Santos Lígia Ramos, Trancozo Maira, de Paula Flavia
Abstract excerpt
Genome-wide association studies (GWAS) have associated several genetic variants with late-onset Alzheimer's disease (LOAD), a neurodegenerative disease. Among those, rs3764650 ABCA7, rs6656401 CR1, and rs744373 BIN1 were associated as risk factors for LOAD, while rs11136000 CLU and rs610932 MS4A6A were protective. Recently, several case-control studies have investigated the association of these polymorphisms with...
