Article
Clenbuterol Attenuates hERG Channel by Promoting the Mature Channel Degradation.
International journal of toxicology - 1 Jan 2000
Luo Ling, Hu Peijing, Miao Changqing, Ma Aiqun, Wang Tingzhong
Abstract excerpt
Clenbuterol, a β2-selective adrenergic receptor agonist, is illicitly used in weight loss and performance enhancement and animal production. Increasing evidence demonstrates that clenbuterol induces various kinds of arrhythmias and QTc interval prolongation. However, little is known about the underlying mechanism. Most drugs are associated with QTc prolongation through interfering with human ether-a-go-go-related...
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