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Article

Comparison of the effects of antiarrhythmic drugs flecainide and verapamil on fKv1.4ΔN channel currents in Xenopus oocytes.

Acta pharmacologica Sinica - 1 Feb 2013

Chen Hui, Zhang Dong, Chao Sheng-ping, Ren Jiang-hua, Xu Lin, Jiang Xue-jun, Wang Shi-min

Abstract excerpt

AIM: To study the effects of Na(+) channel blocker flecainide and L-type Ca(2+) channel antagonist verapamil on the voltage-gated fKv1.4ΔN channel, an N-terminal-deleted mutant of the ferret Kv1.4 K(+) channel. METHODS: fKv1.4ΔN channels were stably expressed in Xenopus oocytes. The K(+) currents were recorded using a two-electrode voltage-clamp technique. The drugs were administered through superfusion. RESULTS:...

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Identifiers

PMID: 23202797
DOI: 10.1038/aps.2012.157
PMCID: PMC4011620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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