Causal relationship between multiple sclerosis and cortical structure: a Mendelian randomization study.

Abstract excerpt

BACKGROUND: Observational studies have suggested an association between multiple sclerosis (MS) and cortical structure, but the results have been inconsistent. OBJECTIVE: We used two-sample Mendelian randomization (MR) to assess the causal relationship between MS and cortical structure. METHODS: MS data as the exposure trait, including 14,498 cases and 24,091 controls, were obtained from the International...

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• Brain Diseases
• Causality
• Genome-Wide Association Study
• Mendelian Randomization Analysis
• Multiple Sclerosis