Article
Effects of crack cocaine addiction and stress-related genes on peripheral BDNF levels.
Journal of psychiatric research - 1 Jul 2017
Rovaris Diego L, Schuch Jaqueline B, Grassi-Oliveira Rodrigo, Sanvicente-Vieira Breno, da Silva Bruna S, Walss-Bass Consuelo, Müller Diana, Stolf Anderson R, von Diemen Lisia, Ceresér Keila M M, Pianca Thiago G, Szobot Claudia M, Kessler Felix H P, Roman Tatiana, Bau Claiton H D
Abstract excerpt
This study examined the effects of glucocorticoid receptor (NR3C1), corticotropin-releasing hormone receptor 1 (CRHR1), and brain-derived neurotrophic factor (BDNF) genes on susceptibility to crack cocaine addiction and BDNF levels. Crack addicted patients who sought treatment (n = 280) and non-addicted individuals (n = 241) were assessed. Three SNPs in NR3C1 (rs6198, rs41423247, and rs10052957), three in CRHR1...
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