Genetic variation in BDNF is associated with opioid use disorder severity.

doi:10.1007/s00439-026-02866-x

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Article

Genetic variation in BDNF is associated with opioid use disorder severity.

Human genetics - 19 Sept 2026

Kusic Dara M, Salzman Matthew, Heil Jessica, Grant Struan F A, Trang Khanh B, Zajic Stefan, Madzo Jozef, Brown Christian, Jelinek Jaroslav, Calendo Gennaro, Schwarting Roland, Issa Jean-Pierre J, Scheinfeldt Laura B

Abstract excerpt

As the opioid epidemic continues to challenge local communities in the United States, scientists, clinicians, and community stakeholders are seeking to understand the myriad factors that contribute to misuse in order to develop effective preventions and treatments. Among these efforts is the Camden Opioid Research Initiative (CORI) that aims to identify and characterize genetic and non-genetic risk factors for...

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Topics

Humans
Brain-Derived Neurotrophic Factor
Polymorphism, Single Nucleotide
Opioid-Related Disorders
Female

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Linkage Disequilibrium

Genetic Predisposition to Disease

Male

Genotype

Adult

Severity of Illness Index

Genetic Variation

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 42762342
DOI: 10.1007/s00439-026-02866-x
PMCID: PMC13589716

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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