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Article

Corticosteroid receptor genes and childhood neglect influence susceptibility to crack/cocaine addiction and response to detoxification treatment.

Journal of psychiatric research - 1 Sept 2015

Rovaris Diego L, Mota Nina R, Bertuzzi Guilherme P, Aroche Angelita P, Callegari-Jacques Sidia M, Guimarães Luciano S P, Pezzi Júlio C, Viola Thiago W, Bau Claiton H D, Grassi-Oliveira Rodrigo

Abstract excerpt

The aim of this study was to analyze hypotheses-driven gene-environment and gene-gene interactions in smoked (crack) cocaine addiction by evaluating childhood neglect and polymorphisms in mineralocorticoid and glucocorticoid receptor genes (NR3C2 and NR3C1, respectively). One hundred thirty-nine crack/cocaine-addicted women who completed 3 weeks of follow-up during early abstinence composed our sample. Childhood...

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Source

Identifiers

PMID: 26228405
DOI: 10.1016/j.jpsychires.2015.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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