Article
Ethnic-specific genetic association of variants in the corticotropin-releasing hormone receptor 1 gene with nicotine dependence.
BioMed research international - 1 Jan 2015
Tang Xiujun, Zhan Shumin, Yang Liping, Cui Wenyan, Ma Jennie Z, Payne Thomas J, Li Ming D
Abstract excerpt
Twin and family studies indicate that smoking addiction is highly influenced by genetic factors. Variants in the corticotropin-releasing hormone receptor 1 (CRHR1) gene have been associated with alcoholism and depression. In this study, we tested five single nucleotide polymorphisms (SNPs) in CRHR1 for their association with ND, which was assessed by smoking quantity (SQ), the Heaviness of Smoking Index (HSI),...
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