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Article

A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction.

PloS one - 1 Jan 2018

Levran Orna, Correa da Rosa Joel, Randesi Matthew, Rotrosen John, Adelson Miriam, Kreek Mary Jeanne

Abstract excerpt

Dysregulation of the stress response is implicated in drug addiction; therefore, polymorphisms in stress-related genes may be involved in this disease. An analysis was performed to identify associations between variants in 11 stress-related genes, selected a priori, and heroin addiction. Two discovery samples of American subjects of European descent (EA, n = 601) and of African Americans (AA, n = 400) were...

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Topics

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Share to CRH gene
Share to Heroin Dependence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait, Heritable

Share to Receptors, Corticotropin-Releasing Hormone

Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 29953524
DOI: 10.1371/journal.pone.0199951
PMCID: PMC6023117

Genes

CRHR2
CRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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