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Article

Distinct profiles of TERT promoter mutations and telomerase expression in head and neck cancer and cervical carcinoma.

International journal of cancer - 1 Sept 2018

Annunziata Clorinda, Pezzuto Francesca, Greggi Stefano, Ionna Franco, Losito Simona, Botti Gerardo, Buonaguro Luigi, Buonaguro Franco M, Tornesello Maria Lina

Abstract excerpt

Two recurrent mutations (-124 G > A and -146 G > A) in the core promoter region of the human telomerase reverse transcriptase (TERT) gene create consensus binding sites for ETS transcription factors and cause increased TERT expression in several tumour types. We analyzed TERT promoter mutations and TERT mRNA levels in head and neck cancer, cervical carcinoma and cervical intraepithelial neoplasia (CIN) as well as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29603728
DOI: 10.1002/ijc.31412

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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