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Article

TERT promoter mutations are associated with poor prognosis in cutaneous squamous cell carcinoma.

Journal of the American Academy of Dermatology - 1 Mar 2019

Campos Manuel António, Macedo Sofia, Fernandes Margarida, Pestana Ana, Pardal Joana, Batista Rui, Vinagre João, Sanches Agostinho, Baptista Armando, Lopes José Manuel, Soares Paula

Abstract excerpt

BACKGROUND: Telomerase reverse transcriptase gene (TERT) promoter (TERTp) mutations have been reported as potential predictors of poor prognosis in several cancers, but the prognostic value of TERTp mutations for cutaneous squamous cell carcinoma (cSCC) has not been determined. OBJECTIVE: To evaluate the frequency of TERTp mutations and correlate it with clinicopathologic features and patient outcome. METHODS: We...

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Identifiers

PMID: 30165166
DOI: 10.1016/j.jaad.2018.08.032

Genes

TERT

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