Common Chemical Inductors of Replication Stress: Focus on Cell‐Based Studies

doi:10.3390/biom7010019

Article

Common Chemical Inductors of Replication Stress: Focus on Cell‐Based Studies

21 Feb 2017

Abstract excerpt

DNA replication is a highly demanding process regarding the energy and material supply and must be precisely regulated, involving multiple cellular feedbacks. The slowing down or stalling of DNA synthesis and/or replication forks is referred to as replication stress (RS). Owing to the complexity and requirements of replication, a plethora of factors may interfere and challenge the genome stability, cell survival...

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