Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DNA replication stress and cancer chemotherapy

23 Nov 2017

Abstract excerpt

DNA replication is one of the fundamental biological processes in which dysregulation can cause genome instability. This instability is one of the hallmarks of cancer and confers genetic diversity during tumorigenesis. Numerous experimental and clinical studies have indicated that most tumors have experienced and overcome the stresses caused by the perturbation of DNA replication, which is also referred to as DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29168596
DOI: 10.1111/cas.13455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DNA replication stress and cancer chemotherapyPMID 29168596Read ↗

Targeting DNA Replication Stress for Cancer TherapySemantic proximity Read ↗

DNA replication stress and cancer: cause or cure?Semantic proximity Read ↗

DNA replication stress as a hallmark of cancer.Semantic proximity Read ↗

DNA replication stress: oncogenes in the spotlightSemantic proximity Read ↗

DNA replication stress: oncogenes in the spotlightSemantic proximity Read ↗

Exploiting DNA Replication Stress as a Therapeutic Strategy for Breast CancerSemantic proximity Read ↗

Therapeutic Targeting of DNA Replication Stress in CancerSemantic proximity Read ↗

Targeting Replication Stress Response Pathways to Enhance Genotoxic Chemo- and RadiotherapySemantic proximity Read ↗

Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11Semantic proximity Read ↗

Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.Semantic proximity Read ↗

Common Chemical Inductors of Replication Stress: Focus on Cell‐Based StudiesSemantic proximity Read ↗

DNA replication stress: Causes, resolution and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.