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Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11

14 Sept 2021

Abstract excerpt

Precision medicine aims to implement strategies based on the molecular features of tumors and optimized drug delivery to improve cancer diagnosis and treatment. DNA replication is a logical approach because it can be targeted by a broad range of anticancer drugs that are both clinically approved and in development. These drugs increase deleterious replication stress (RepStress); however, how to selectively target...

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PMID: 34572827
DOI: 10.3390/cancers13184601

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