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DNA replication stress: Causes, resolution and disease

1 Oct 2014

Abstract excerpt

DNA replication is a fundamental process of the cell that ensures accurate duplication of the genetic information and subsequent transfer to daughter cells. Various pertubations, originating from endogenous or exogenous sources, can interfere with proper progression and completion of the replication process, thus threatening genome integrity. Coordinated regulation of replication and the DNA damage response is...

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PMID: 25281304
DOI: 10.1016/j.yexcr.2014.09.030

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