Article
DNA replication stress and cancer: cause or cure?
Future oncology (London, England) - 1 Jan 2016
Taylor Elaine M, Lindsay Howard D
Abstract excerpt
There is an extensive and growing body of evidence that DNA replication stress is a major driver in the development and progression of many cancers, and that these cancers rely heavily on replication stress response pathways for their continued proliferation. This raises the possibility that the pathways that ordinarily protect cells from the accumulation of cancer-causing mutations may actually prove to be...
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