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Article

C-edge loops of arrestin function as a membrane anchor.

Nature communications - 21 Feb 2017

Lally Ciara C M, Bauer Brian, Selent Jana, Sommer Martha E

Abstract excerpt

G-protein-coupled receptors are membrane proteins that are regulated by a small family of arrestin proteins. During formation of the arrestin-receptor complex, arrestin first interacts with the phosphorylated receptor C terminus in a pre-complex, which activates arrestin for tight receptor binding. Currently, little is known about the structure of the pre-complex and its transition to a high-affinity complex....

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Identifiers

PMID: 28220785
DOI: 10.1038/ncomms14258
PMCID: PMC5321764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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