Differential phosphorylation of the rhodopsin cytoplasmic tail mediates the binding of arrestin and its splice variant, p44.

Abstract excerpt

Deactivation of the vertebrate photopigment rhodopsin is achieved through a two-step process. Rhodopsin is first phosphorylated by rhodopsin kinase and subsequently deactivated by the binding of the regulatory protein arrestin or its splice variant, p44. Although much is known about the overall differences between arrestin and p44 binding to different rhodopsin species (photolyzed versus unphotolyzed and/or...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alternative Splicing
• Share to Amino Acid Substitution
• Share to Arrestin