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Article

Receptor-Arrestin Interactions: The GPCR Perspective.

Biomolecules - 4 Feb 2021

Seyedabadi Mohammad, Gharghabi Mehdi, Gurevich Eugenia V, Gurevich Vsevolod V

Abstract excerpt

Arrestins are a small family of four proteins in most vertebrates that bind hundreds of different G protein-coupled receptors (GPCRs). Arrestin binding to a GPCR has at least three functions: precluding further receptor coupling to G proteins, facilitating receptor internalization, and initiating distinct arrestin-mediated signaling. The molecular mechanism of arrestin-GPCR interactions has been extensively...

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Identifiers

PMID: 33557162
DOI: 10.3390/biom11020218
PMCID: PMC7913897

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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