Article
Absence of the frequently reported PIK3CA, CASP8, and NOTCH1 mutations in South Indian oral cancers.
Oral diseases - 1 Jul 2017
Arunkumar G, Murugan A K, Nagarajan M, Ajay C, Rajaraman R, Munirajan A K
Abstract excerpt
OBJECTIVES: Somatic mutations of the PIK3CA, CASP8, and NOTCH1 have been frequently detected in various human cancers. Our study aimed to analyze the mutational status of these genes in South Indian oral cancers. SUBJECTS AND METHODS: We performed mutational analysis of the PIK3CA (exons 9 and 20), CASP8 (exon 9), and NOTCH1 (exons 5, 6, 7, 8, and 9) genes in 96, 48, and 44 oral cancer samples, respectively. All...
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