Article
Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression.
PloS one - 1 Jan 2020
Singh Richa, Das Shreya, Datta Sila, Mazumdar Anjana, Biswas Nidhan K, Maitra Arindam, Majumder Partha P, Ghose Sandip, Roy Bidyut
Abstract excerpt
It is hypothesized that same driver gene mutations should be present in both oral leukoplakia and cancer tissues. So, we attempted to find out mutations at one of the driver genes, CASP8, in cancer and adjacent leukoplakia tissues. Patients (n = 27), affected by both of cancer and adjacent leukoplakia, were recruited for the study. Blood and tissue DNA samples were used to identify somatic mutations at CASP8 by...
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