Article
Novel mutations of PIK3CA gene in head and neck squamous cell carcinoma.
Cancer biomarkers : section A of Disease markers - 1 Jan 2016
Al-Amri Ali M, Vatte Chittibabu, Cyrus Cyril, Chathoth Shahanas, Hashim Tariq Mohammad, Mohamed Yehia S, Al Ali Rudaynah, Alsaid Abir, Al Ali Amein
Abstract excerpt
BACKGROUND: HNSCC is the sixth most common human cancer globally. In Saudi Arabia, HNSCC accounts for seven percent of all newly diagnosed cancer cases. The PIK3CA is one of the most commonly mutated oncogene in human malignancies, including HNSCC. OBJECTIVE: The objective of this study is to identify mutations in exon 9 and exon 20 of the PIK3CA gene among Saudi HNSCC patients, determine the frequency of these...
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