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Article

Genetic alterations of the PIK3CA oncogene in human oral squamous cell carcinoma in an Indian population.

Oral surgery, oral medicine, oral pathology and oral radiology - 1 Nov 2015

Shah Sejal, Shah Siddharth, Padh Harish, Kalia Kiran

Abstract excerpt

OBJECTIVE: The phosphatidylinositol 3-kinase (PIK3) genes, which code for heterodimeric lipid kinases, consist of a catalytic subunit, p110α (PIK3CA), which regulates cell proliferation, apoptosis, and metastasis. Recently, a high frequency of somatic mutations was observed in the PIK3CA gene in various cancer types, including oral squamous cell carcinoma (OSCC). This study aimed to determine the frequency of...

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Identifiers

PMID: 26453385
DOI: 10.1016/j.oooo.2015.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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