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Article

Polymorphisms in NQO1 and MPO genes and risk for bladder cancer in Tunisian population.

Molecular genetics & genomic medicine - 1 Nov 2021

Hemissi Imen, Ayed Haroun, Naimi Zeineb, Meddeb Khedija, Ayadi Mouna, Zouari Skander, Zaghbib Selim, Talbi Emna, Chebil Mohamed, Ouerhani Slah

Abstract excerpt

BACKGROUND: NAD (P) H: quinone oxidoreductase (1) (NQO1-HGNC: 2874) and myeloperoxidase (MPO-HGNC: 7218) are two enzymes involved in phase II of the xenobiotic metabolism pathway. METHODS: In this study, a case-control analysis was conducted to investigate the relationship between genetic variations in the NQO1 (C609T, rs1800566; IVS1-27 C >G, rs689452) and MPO (G463A, rs2333227) genes and the risk for bladder...

Topics

Case-Control Studies
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

NAD(P)H Dehydrogenase (Quinone)

Polymorphism, Genetic

Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 34549902
DOI: 10.1002/mgg3.1819
PMCID: PMC8606214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34549902-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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