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Article

Increased risk of bladder cancer associated with a glutathione peroxidase 1 codon 198 variant.

The Journal of urology - 1 Aug 2004

Ichimura Yasushi, Habuchi Tomonori, Tsuchiya Norihiko, Wang Lizhong, Oyama Chikara, Sato Kazunari, Nishiyama Hiroyuki, Ogawa Osamu, Kato Tetsuro

Abstract excerpt

PURPOSE: The glutathione peroxidase 1 gene (GPX1) and the manganese superoxide dismutase gene (MnSOD) encode the main antioxidant enzymes that detoxify endogenous reactive oxygen species involved in carcinogenesis. Polymorphisms of GPX1 and MnSOD genes, and the risk of transitional cell cancer of the bladder were tested. MATERIALS AND METHODS: Genotypes of the leucine (Leu) to proline (Pro) polymorphism at codon...

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Source

Identifiers

PMID: 15247771
DOI: 10.1097/01.ju.0000130942.40597.9d

Genes

GPX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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