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Article

Genetic variants of MnSOD and GPX1 and susceptibility to bladder cancer in a Turkish population.

Medical oncology (Northwood, London, England) - 1 Sept 2012

Kucukgergin Canan, Sanli Oner, Amasyalı Akın S, Tefik Tzevat, Seckin Sule

Abstract excerpt

This study was conducted to investigate the association of genetic polymorphisms in the MnSOD and GPX1 genes with the risk and invasiveness of bladder cancer in a Turkish population. This prospectively designed study enrolled 157 patients with bladder cancer (mean age 63.2 ± 10.86 years) and 224 healthy controls (mean age 61.7 ± 8.39 years). Genotyping of the MnSOD Ala-9Val and GPX1 Pro198Leu polymorphisms was...

Topics

Carcinoma, Transitional Cell
Female
Genetic Predisposition to Disease
Genotype
Glutathione Peroxidase
Humans
Male
Middle Aged
Polymorphism, Restriction Fragment Length
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Reverse Transcriptase Polymerase Chain Reaction

Superoxide Dismutase

Turkey

Urinary Bladder Neoplasms

Glutathione Peroxidase GPX1

Source

Identifiers

PMID: 21904836
DOI: 10.1007/s12032-011-0057-z

Genes

GPX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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