Article
DNA repair gene polymorphisms and bladder cancer susceptibility in a Turkish population.
Anticancer research - 1 Jan 2000
Karahalil Bensu, Kocabas Neslihan Aygün, Ozçelik Tayfun
Abstract excerpt
BACKGROUND: Occupational exposure and life style preferences, such as smoking are the main known environmental susceptibility factors for bladder cancer. A growing list of chemicals has been shown to induce oxidative DNA damage. Base excision repair (BER) genes (X-ray repair cross complementing 1, XRCC1 and human 8-oxoguanine DNA glycosylase 1, OGG1) may play a key role in maintaining genome integrity and...
Topics
- Adult
- Aged
- Aged, 80 and over
- DNA Glycosylases
- DNA Repair
- DNA-Binding Proteins
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Turkey
- Urinary Bladder Neoplasms
- X-ray Repair Cross Complementing Protein 1
