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Article

Iterative sure independence screening EM-Bayesian LASSO algorithm for multi-locus genome-wide association studies.

PLoS computational biology - 1 Jan 2017

Tamba Cox Lwaka, Ni Yuan-Li, Zhang Yuan-Ming

Abstract excerpt

Genome-wide association study (GWAS) entails examining a large number of single nucleotide polymorphisms (SNPs) in a limited sample with hundreds of individuals, implying a variable selection problem in the high dimensional dataset. Although many single-locus GWAS approaches under polygenic background and population structure controls have been widely used, some significant loci fail to be detected. In this...

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PMID: 28141824
DOI: 10.1371/journal.pcbi.1005357
PMCID: PMC5308866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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