Article
A model-free approach for detecting interactions in genetic association studies.
Briefings in bioinformatics - 1 Nov 2014
Li Jiahan, Dan Jun, Li Chunlei, Wu Rongling
Abstract excerpt
Over the past few decades, genome-wide association studies analyzed by efficient statistical procedures have successfully identified single-nucleotide polymorphisms (SNPs) that are associated with complex traits or human diseases. However, due to the overwhelming number of SNPs, most approaches have focused on additive genetic model without genome-wide SNP-SNP interactions. In this study, we propose an efficient...
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