Article
pLARmEB: integration of least angle regression with empirical Bayes for multilocus genome-wide association studies.
Heredity - 1 Jun 2017
Zhang J, Feng J-Y, Ni Y-L, Wen Y-J, Niu Y, Tamba C L, Yue C, Song Q, Zhang Y-M
Abstract excerpt
Multilocus genome-wide association studies (GWAS) have become the state-of-the-art procedure to identify quantitative trait nucleotides (QTNs) associated with complex traits. However, implementation of multilocus model in GWAS is still difficult. In this study, we integrated least angle regression with empirical Bayes to perform multilocus GWAS under polygenic background control. We used an algorithm of model...
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