Article
GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies.
Bioinformatics (Oxford, England) - 1 Jan 2019
Sanyal Nilotpal, Lo Min-Tzu, Kauppi Karolina, Djurovic Srdjan, Andreassen Ole A, Johnson Valen E, Chen Chi-Hua
Abstract excerpt
Motivation: Multiple marker analysis of the genome-wide association study (GWAS) data has gained ample attention in recent years. However, because of the ultra high-dimensionality of GWAS data, such analysis is challenging. Frequently used penalized regression methods often lead to large number of false positives, whereas Bayesian methods are computationally very expensive. Motivated to ameliorate these issues...
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