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Article

Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies.

PLoS genetics - 25 Jul 2008

Hoggart Clive J, Whittaker John C, De Iorio Maria, Balding David J

Abstract excerpt

Testing one SNP at a time does not fully realise the potential of genome-wide association studies to identify multiple causal variants, which is a plausible scenario for many complex diseases. We show that simultaneous analysis of the entire set of SNPs from a genome-wide study to identify the subset that best predicts disease outcome is now feasible, thanks to developments in stochastic search methods. We used a...

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Identifiers

PMID: 18654633
DOI: 10.1371/journal.pgen.1000130
PMCID: PMC2464715

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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