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Article

Powerful Identification of Large Quantitative Trait Loci Using Genome-Wide R/glmnet-Based Regression.

The Journal of heredity - 23 Jul 2022

Yang Li'ang, Qu Qiannan, Hao Zhiyu, Sha Ke, Li Ziyu, Li Shuling

Abstract excerpt

R/glmnet has been successfully applied to jointly mapped multiple quantitative trait loci for linkage analysis, along with statistical inference for quantitative trait loci candidates with nonzero genetic effects using R/lm for normally distributed traits, R/glm for discrete traits, and R/coxph for survival times. In this study, we extended R/glmnet to a genome-wide association study by means of parallel...

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PMID: 35134967
DOI: 10.1093/jhered/esac006

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