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Article

Rapamycin additively extends lifespan in short- and long-lived lines of the nematode Caenorhabditis remanei.

Experimental gerontology - 1 Apr 2017

Lind Martin I, Chen Hwei-Yen, Cortazar-Chinarro Maria, Maklakov Alexei A

Abstract excerpt

Despite tremendous progress in finding genes that, when manipulated, affects lifespan, little is known about the genetics underlying natural variation in lifespan. While segregating genetic variants for lifespan has been notoriously difficult to find in genome-wide association studies (GWAS), a complementary approach is to manipulate key genetic pathways in lines that differ in lifespan. If these candidate...

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PMID: 28119053
DOI: 10.1016/j.exger.2017.01.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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