Article
Longevity determined by developmental arrest genes in Caenorhabditis elegans.
Aging cell - 1 Aug 2007
Chen Di, Pan Kally Z, Palter Julia E, Kapahi Pankaj
Abstract excerpt
The antagonistic pleiotropy theory of aging proposes that aging takes place because natural selection favors genes that confer benefit early on life at the cost of deterioration later in life. This theory predicts that genes that impact development would play a key role in shaping adult lifespan. To better understand the link between development and adult lifespan, we examined the genes previously known to be...
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