Article
Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster.
The journals of gerontology. Series A, Biological sciences and medical sciences - 13 Nov 2019
Gubina Nina, Naudi Alba, Stefanatos Rhoda, Jove Mariona, Scialo Filippo, Fernandez-Ayala Daniel J, Rantapero Tommi, Yurkevych Ihor, Portero-Otin Manuel, Nykter Matti, Lushchak Oleh, Navas Placido, Pamplona Reinald, Sanz Alberto
Abstract excerpt
Aging is a multifactorial process which affects all animals. Aging as a result of damage accumulation is the most accepted explanation but the proximal causes remain to be elucidated. There is also evidence indicating that aging has an important genetic component. Animal species age at different rates and specific signaling pathways, such as insulin/insulin-like growth factor, can regulate life span of...
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