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Article

Multimerization properties of PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements.

Nucleic acids research - 7 Apr 2017

Dubois Emeline, Mathy Nathalie, Régnier Vinciane, Bischerour Julien, Baudry Céline, Trouslard Raphaëlle, Bétermier Mireille

Abstract excerpt

During sexual processes, the ciliate Paramecium eliminates 25-30% of germline DNA from its somatic genome. DNA elimination includes excision of ∼45 000 short, single-copy internal eliminated sequences (IESs) and depends upon PiggyMac (Pgm), a domesticated piggyBac transposase that is essential for DNA cleavage at IES ends. Pgm carries a core transposase region with a putative catalytic domain containing three...

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Identifiers

PMID: 28104713
DOI: 10.1093/nar/gkw1359
PMCID: PMC5389696

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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