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Article

Identification and analysis of functional associations among natural eukaryotic genome editing components

2017-08-08

Abstract excerpt

During development in the ciliate Paramecium, excess DNA interspersed throughout the germline genome is deleted to generate a new somatic genome. In this process, most of the intervening DNA is excised by a Piggybac-derived transposase, assisted by small RNAs (scnRNAs and iesRNAs) and chromatin remodelling. As the list of genes involved in DNA elimination has been growing, a need for a general approach to discove...

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Literature Corpus work
c4750495-3a40-59ee-9680-46a441a4aad0
DOI
10.12688/f1000research.12121.1
Open publication

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Identification and analysis of functional associations among natural eukaryotic genome editing componentsDOI 10.12688/f1000research.12121.1
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